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In some cases, patients can experience skin irritation, redness or minor allergic reactions at the injection site but that is for a brief period.

These mechanisms provide a rationale for long-acting analogs such as liraglutide and semaglutide showing sustained effects on glucose control in laboratory research

Understanding this framework shifts the conversation from blame to informed decision-making

Here, we describe two unrelated Japanese patients with novel RARB variants, which expand our understanding of the clinical and genetic features of MCOPS12

J Endocrinol (2015) 225:R2134