Cubilin and amnionless are the 2 components of the receptor that B12 binds with when it goes up the distal ileum
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10.3390/antiox13020202 238 SunX.ZhangW
It is a living, active system
This process also involves Rubicon (RUN domain protein as Beclin-1 interacting and cysteine-rich containing) activity to stabilize the Class III PI3K complex, at the phagosome