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Thus, miR-124a2 can directly modulate insulin expression through foxA2 and then pdx1

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Whether initiating GLP-1 RAs earlier - either concomitantly with surgery or immediately upon detecting early weight regain - could improve long-term outcomes remains to be investigated

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For locomotor activity test, mice were placed in an activity monitor chamber (20 cm 20 cm 15 cm) to acclimatize for 15 min before the start of the test

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