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This work highlights the role of the gut microbiome and secreted gut hormones in regulating locomotor behavior

SSRIs are a group of drugs that inhibit the SERT and elevate extracellular 5-HT levels in the brain (120)

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Interestingly, interventions that boost NAD + levels resulted in extended lifespan in worms and mice 108,109,111,247 , suggesting a therapeutic potential for raising NAD + in various pathological conditions or age-associated diseases

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