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Maybe if they're showing some signs of dementia that has come on reasonably quickly, then testing B12 levels is not a bad idea

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This would reduce glomerular hydrostatic pressure and initially decrease GFR, an effect that is observed with SGLT2 treatment, but in the long run this decrease in GFR protects the kidney from damage resulting in improved kidney function long-term (139)

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Nurses should check that patients understand the chronic nature of treatment