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This likely explains the large heterogeneity in observed lesions in kidney biopsies in the T2D population

The 10mg dose produced 21.4%, and 5mg produced 16.0%

10.1016/j.bbrc.2021.02.065 93 ZhangZ.MaY.XieC.HeY.WangD.SongH.et al (2025)

Allen said evidence indicates that the GLP-1 drugs do indeed help people lose weight

These medications work in part by slowing digestion, increasing fullness, and reducing appetite

Weight loss does not always equal better healthand for many, these medications can pose nutritional, physical, and psychological challenges that arent worth the risk