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These challenges are summarized in Table 1

Most people respond well to treatment, often with simple surgery, and they have few long-term effects

Reported side effects have included mild injection site reactions or topical irritation in rare cases

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Rare But Potentially Serious Side Effects Hypoglycemia Pancreatitis Thyroid Cancer (Medullary Thyroid Carcinoma) Gallbladder Disease Multiple Endocrine Neoplasia Syndrome Type 2 If you have a personal medical history or family history of thyroid issues or gallbladder disease, you will require careful monitoring and your doctor may advise you to avoid GLP-1 injections altogether

3 (download XLSX Excel workbook with raw data Source Data Extended Data Fig