Some membrane proteins, such as glutamine synthetase (encoding by glnA ) and periplasmic putrescine binding protein (encoding by potE ), are related to the transport of amino acids and can also affect the expression of proteins
1982-11, 243 (5): H691-H697 [2025-12-01]
For example, HSP90 inhibitors such as ganetespib not only disrupt chaperone function but also enhance autophagy, leading to the degradation of oncogenic proteins in cancer
Defects in enzymes that metabolize homocysteine are a primary risk factor for hyperhomocysteinemia.7,9 A summary of the key enzymes responsible for homocysteine metabolism follows
(Very rare but serious side effects include gallstones and pancreatitis

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