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The fixed tissues were dehydrated and embedded in paraffin blocks, and 6 m sections were stained with hematoxylin and eosin (H&E)

Centrilobular (Figures 5459) Sometimes referred to as periacinar necrosis, it consists of irreversible cell death of centrilobular hepatocytes and is often seen after anoxia, or exposure to tannic acid, chloroform, or other hepatotoxic agents (Gopinath, Prentice, and Lewis 1987)

The mitochondrial Na+/Ca2 + exchanger upregulates glucose dependent Ca2 + signalling linked to insulin secretion

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This is a natural process that your body does or should do on its own