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Class explains that unlike with a regular dose, the goal of a microdose isnt appetite shutdown

Like other GLP-1 receptor agonists, retatrutide regulates insulin production and slows gastric emptying, which promotes satiety and reduces appetite

However, both medication classes can cause gastrointestinal side effects, and semaglutide's effect on gastric emptying may require timing considerations for oral medications

However, lower doses may be sufficient depending on individual response

Headaches are a major contributor to reduced quality of life in IIH patients, and cognitive complaints have also been reported to improve when ICP is lowered

The 2mg dose primarily activates GLP-1 with minimal glucagon receptor engagement