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Muscle Loss Prevention Rapid weight loss can cause muscle wasting

A 2014 study found that liraglutide treatment for a minimum of 4 weeks in overweight or obese individuals with PCOS resulted in an average weight loss of 9kg and 81.7% lost at least 5% of their starting body weight

Pak SC, Lim SC, Nah SY, et al

For most patients, taking both is safe with correct timing

Among patients at high cardiovascular risk, the effect estimate was an HR of 0.88 (95% CI 0.73 to 1.07)

Glucagon-like peptide-1 receptor (GLP-1R) is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway