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Reasons why mitochondria might be impaired or damaged include: Aging Inadequate diet Poor sleep Lack of exercise Genetics Heavy and toxic metals Pollutants Free radicals Prescription drugs Alcohol There are many conditions that are caused or made worse by mitochondrial dysfunction, such as the following per Pizzorno (2014): Early aging Amyotrophic lateral sclerosis Alzheimers disease Autism Cardiovascular disease Chronic fatigue syndrome Dementia Diabetes Huntingtons disease Migraine headache Parkinsons disease A great way to directly influence the health of our mitochondria is through the use of peptides

Effects of the HIV protease inhibitor ritonavir on GLUT4 knock-out mice

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Preclinical rodent models (Wessells et al

The advent of selective androgen receptor modulators (SARMs) promises significant therapeutic potential to ameliorate the sarcopenic effect of androgen deprivation therapy in the future

it is also an essential factor in the growth and operation of brain and nerve cells