Common neurological manifestations include: Paraesthesia (pins and needles) in the hands and feet Numbness and altered sensation Difficulty with balance and coordination (ataxia) Memory problems and cognitive impairment Mood changes, including depression and irritability In severe cases, visual disturbances and confusion These neurological features arise from demyelination of peripheral nerves and the spinal cord, a condition known as subacute combined degeneration when it affects the posterior and lateral columns of the spinal cord
Pain Physician 22 (1): E45e52
Sikiric, P., Udovicic, M., Barisic, I., Balenovic, D., Zivanovic Posilovic, G., Strinic, D., Uzun, S., Sikiric, S., Krezic, I., Zizek, H., Yago, H., Gojkovic, S., Smoday, I
This phase often shows the most dramatic improvement as accumulated healing effects become apparent
Do not use as a substitute for evaluation of persistent pain, swelling, gastrointestinal bleeding, or suspected tendon rupture
doi: 10.1016/S1474-4422(20)30342-2 226 YongH