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In a 2021 study published in the New England Journal of Medicine, participants treated with semaglutide lost an average of about 15 percent of their body weight, compared with a loss of 2.4 percent in the placebo group

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Travel-relevant drugs with narrow absorption windows include: Oral contraceptives: consider backup contraception for the first four weeks on tirzepatide or after a dose escalation, per ACOG guidance on GI-motility effects on hormonal contraception [13]