While some studies report positive associations between higher serum 25(OH)D levels and improved cognitive performance [77,80,81], other studies find no significant effects [102,105]
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In line with a previous report 26 , we provide further evidence that CD38 cell-to-cell expression variation level in T cells, which directly reflects their cellular state and is seemingly conserved across mice and humans, could be potentially used as a biomarker in pre-symptomatic AD and other familial neurodegenerative conditions