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In this study, we demonstrate that AKT1-mediated phosphorylation activates PRMT7, which stabilizes GLUD1 through methylation and suppression of ubiquitination, thereby promoting gastric cancer proliferation and metastasis

5.4 Youth and fertility planning: shifting from short-term loss to cross-cycle net benefit Young women with PCOS are often more susceptible to aesthetic pressure and social media influence, potentially viewing GLP-1RAs as a tool for rapid weight management. Concurrently, concerns regarding long-term medication and pregnancy safety often lead to intermittent use and frequent start-stop cycles

Professional medical advice recommending discontinuation

Notably, SCFAs, tryptophan metabolites, and other bacterial byproducts can reach the CNS via the portal and systemic circulation, modulating neuroinflammation, neurotransmitter biosynthesis, and even behavior

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