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A high amount of glutathione (naturally present and through the addition of yeast hulls), combined with significant SO2 additions and a winemaking approach that limits oxygen greatly might indeed result in doing the opposite of what the winemaker was aiming for: preserving the fruit aromas

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N Engl J Med 370(15):13831392 Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ et al (2003) Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial