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When patients ask about longterm risks, be transparent about what is known and unknown
A team led by Luba Yammine, a clinician, and researcher at the University of Texas Health Science Center at Houston, found in 2021 that 46% of patients who wore nicotine patches and received weekly injections of exenatide, a first-generation GLP-1 analog, stopped smoking , versus 27% of people who relied only on the patches. Another study with 127 people with alcohol use disorder who were given exenatide, a GLP-1 agonist, displayed less activity in the brains reward centers on fMRI when shown pictures of alcohol
While reducing body mass index (BMI) does reduce the risk of cancer incidence, it is not to the extent that lowering BMI reduces mortality risk
[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Patti M.E., Butte A.J., Crunkhorn S., Cusi K., Berria R., Kashyap S., Miyazaki Y., Kohane I., Costello M., Saccone R., et al
McQuerry, and A