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Kang HJ, Chen N, Dash BC, Hsia HC, Berthiaume F

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

Vitamin A (retinol) is important for the function of the immune system due to its anti-inflammatory effects

Scientists continue to investigate how this shift may contribute to changes in energy production, recovery, immune function, and overall cellular health as we get older

The liver and kidneys are two of the main detoxification organs in the body

Crucially, FOXO4-DRI selectively induced apoptosis in senescent TM3 Leydig cells by causing nuclear exclusion of active Ser15-phospho-p53, leading to a significant increase in apoptosis rate and altering pro-apoptotic (BAX, cleaved-Caspase3 increase) and anti-apoptotic (BCL-2 decrease) protein levels