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Rojas et al., 2014) in autism, though more recent reports failed to find Glu and GABA differences in autism(Brix et al., 2015

About 1020% of patients are non-responders or modest responders

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Cardiovascular outcome trials have demonstrated significant reductions in major adverse cardiovascular events with certain agents in this class (liraglutide, injectable semaglutide, and dulaglutide), leading to expanded indications for cardiovascular risk reduction

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