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The study is registered in PROSPERO: Similar content being viewed by others 1 Introduction Glucagon-like peptide 1 receptor agonists (GLP1RAs) are widely used in the treatment of diabetes mellitus (DM) and obesity [1, 2]

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The three key constants elimination half-life (~147 h), absorption rate (k a 0.065 h), and apparent volume of distribution (V z /F 8.3 L) come from Phase 1 clinical trial data published in Cell Metabolism

Clinical safety data management: definitions and standards for expedited reporting (E2a)

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