Insurance coverage, availability and affordability are likely to dictate agent selection
Novo Nordisk's investigational triple agonist UBT251 (targeting GLP-1, GIP, and glucagon) delivered up to 19.7% mean weight loss in just 24 weeks in a Phase 2 trial conducted in China
Once reconstituted with bacteriostatic water, tolerance drops drastically: the solution must stay between 28C or degradation begins within hours
A smaller percentage (29%) experienced mental side effects such as brain fog, mood swings, or anxiety
Commonly prescribed GLP-1 medications in the UK include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), lixisenatide (Lyxumia) and exenatide (Byetta, Bydureon)
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