glp 1 science Glucagon-like Peptide-1 Receptor Agonists: Possible Panacea? Science's 2023 Breakthrough: GLP-1 Agonists

Semaglutide provides a sustainable, long-term solution that repairs metabolic function

If you need to take a urine drug test, tell the person giving the test that you take Contrave, as it can make the test show a positive result for amphetamines

Neurology (1999) 53(9):193742

These results follow similar findings from the companys ATTAIN-1 trial released earlier this month, which tested the drug on people who were overweight or obese without type 2 diabetes (in general, people without diabetes tend to lose more weight from GLP-1 therapy than those with diabetes)

However, the drug was subsequently overtaken by Pfizers Lipitor (FDA-approved in 1996), which generated ~$100B in sales from 1992 to 2017

Last reviewed: June 18, 2026 Last updated: June 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations