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Vicious cycle: high glucose-induced formaldehyde generation and formaldehyde-elicited hyperglycemia Injection of formaldehyde induces an elevation in blood glucose Existing studies have found that injection of formaldehyde at high levels (Formalin) indeed induces a sharp rise in blood glucose ( hyperglycemia ) in the Carp [56], salmon (Salmo salar) and rainbow trout (Salmo gairdneri) [57], and mice [58]