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87 In mice, administering phloretin increased the GLP-1 response and inhibited the GIP response, possibly due to GLUT2 inhibition in K cells

However, mutant IDH enzymes convert -KG into R-2-HG with the oxidation of NADPH into NADP +

Ma -L-L, Wang -Y-Y, Yang Z-H, Huang D, Weng H, Zeng X-T

Despite their limited number, neurons in the caudal brainstem that synthesize GLP-1 have widely-branching axons that innervate multiple brain regions where GLP-1R is expressed, Rinaman noted

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