Both TrxR1 and TrxR2 isoenzymes have a nearly ubiquitous distribution in mammalian tissues
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It has been reported that acetaminophen injection led to a significant release of intracellular iron and subsequent ROS accumulation by activating ferritinophagy on the one hand and inhibiting the endogenous nuclear factor E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) antioxidant pathway on the other hand, which contributes to clear intracellular ROS
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Iron deficiency in athletes: Prevalence and impact on VO2 peak
et al., 2023) the cAMP/PKA/p-CREB pathway was altered in the amygdala alongside neuronal apoptosis (Jiang et al., 2023), and cortical cytokinesincluding IL-1, IL-6, and TNF- were elevated (Wang J
