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It facilitates the reciprocal exchange of intracellular glutamate and extracellular cystine in a 1:1 ratio, ushering cystine entry into the cell

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This dual mechanism earned it FDA approval under the brand names Mounjaro (for type 2 diabetes) and Zepbound (for obesity)

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It's a trace mineral involved in several enzyme systems that help process sulfur-containing compounds, including sulfites.47 Because NAC itself is a sulfur-containing molecule, there's a reasonable biological rationale for pairing the two ingredients