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doi:10.1113/EP085546 da Rosa DP, Forgiarini LF, e Silva MB, et al

doi: 10.1016/s0733-8627(05)70205-4

In high L-arginine-dependent tumors, such as breast cancer (Abdelmagid et al., 2011), CRC (Lu et al., 2013), and HCC (Kishikawa et al., 2015), increased expression of the transporter CAT-1 ( SLC7A1 ) has been observed, and CAT-1 ( SLC7A1 ) knockdown decreases the viability of cancer cells and induces apoptosis

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