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Animal models show gastrointestinal protection, but systemic absorption data in humans remain insufficient

MOTS-C side effects are more closely tied to acute metabolic shifts, like transient changes in blood glucose levels

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Reconstitution: The lipidated structure requires careful reconstitution to achieve a monomeric, soluble preparation

Liraglutide (Victoza and Saxenda) doesnt work as well (produces less weight loss) and causes more side effects, but it is a GLP-1 agonist

Naik, MD, MHSc , president of the HS Foundation, and Diana Thiara, MD, medical director of the weight management program and director of the obesity medicine fellowship at UCSF, wrote in a related editorial published in JAMA Dermatology