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The net reaction is as follows: 3 Glucose 6-phosphate + 6 NADP + + 5 NAD + + 5 P i + 8 ADP 5 Pyruvate + 3 CO 2 + 6 NADPH + 5 NADH + 8 ATP + 2 H 2 O + 8 H + If the cell requires additional ATP, the pyruvate produced can be further oxidized via the citric acid cycle

Mutat Res/Fundamental Mol Mech Mutagen 376(12):115122 Zheng S, Yang H, Zhang S, Wang X, Yu L, Lu J, Li J (1997) Initial study on naturally occurring products from traditional Chinese herbs and vegetables for chemoprevention

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