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The primary mechanism involves slowing gastric emptying and enhancing satiety signals to the brain, leading to significant appetite suppression [3]

Hunt SA, Baker DW, Chin MH, et ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary

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Objective biochemical markers like alanine aminotransferase and aspartate aminotransferase, abbreviated ALT and AST, most often improve in clinical trials within eight to twelve weeks