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Lipid dyshomeostasis interacts with several AD pathogenic pathways, including amyloidogenesis, mitochondrial dysfunction, oxidative stress, neuroinflammation, and myelin degeneration (Yin, 2023

Subsequently, structural modelling and refinement were performed using COOT and REFMAC5 33,34

Additionally, patients who received semaglutide and had concomitant hypertension demonstrated an increased risk for NAION (HR = 2.42

The absence of ADC biosimilar guidance from FDA is an implicit deterrent to development investment

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After propensity-score matching, the two cohorts (26,566 in each cohort, mean age 51.2 years, 65.9% women, 15.8% black, 66.6% white, 6.5% Hispanic) were balanced (Table 1)