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Trauma to the distal phalanx can cause a subungual exostosis, which often causes nail plate deformity, and an osseous injury to the distal phalanx can cause callus formation that can affect the new toenail

8 th week) in patients with MALSD

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Signal transduction Transient signals induced by interactions of cell surface receptors and ligands are translated into prolonged alterations in the gene expression profile by various signaling pathways, entailing reversible assembly of numerous factors