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As a precaution, women planning a pregnancy are advised to consult their physician before use

Further arguments might include modulatory effects on the NO system (NO releasesBPC 157 induced the NO release on its ownparticular effect on NOS inhibition (i.e., opposed hypertension and pro-thrombotic effect of L-NAME) and particular effect on NO over-stimulation (i.e., opposed hypotension and anti-thrombotic, pro-bleeding effect of L-arginine) [39,40,41,42,43,44] controlling vasomotor tone and the activation of Src-Caveolin-1-eNOS pathway [48,49])