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Redox Signaling: Analyzing the molecular mechanisms of cellular electron transfer and oxidative defense

In the next step, isocitrate dehydrogenase (IDH) metabolizes isocitrate to -ketoglutarate (-KG), which is further metabolized to succinyl-CoA by -KG dehydrogenase complex

Among these, ESPEN specifically recommends long-term oral BCAA supplementation at 0.25 g/kg/day in patients with advanced cirrhosis to improve event-free survival and quality of life [11]

10.1002/jcp.21852 21 LollP