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References: Matheson EM, et al

As we age or endure chronic stress, mitochondrial efficiency declinesleading to fatigue, impaired cellular repair, and systemic inflammation

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9 However, uric acid will be transformed into a pro-oxidant and pro-inflammatory molecule that exacerbates oxidative stress when the UA levels are increased

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Size exclusion chromatography (SEC) was done on a customized AEKTA Pure (Cytiva) in 20 mM HEPES, 300 mM NaCl, 5 mM arginine, 5 mM glutamate using a Superose 6 Inc