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Treatment response should be assessed through improvements in OSA-related outcomes, including symptom burden, sleep quality, and overall clinical status, while also monitoring for adverse effects associated with therapy

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The weight-reducing effects of centrally administered GIP are primarily mediated through interactions with GABAergic neurons in regions such as the ARC of the hypothalamus

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Future research should prioritize strategies to optimize maintenance therapy, define the appropriate treatment duration, evaluate long-term safety, and identify patient characteristics associated with durable response

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Its GLP-1 receptor agonist helps release more insulin and reduce glucagon levels

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