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In pivotal STEP trials, approximately 20-25% of semaglutide users reported diarrhea at some point during treatment, with most cases mild to moderate
Clinical investigation has extended to organ transplant recipients, who face dramatically elevated skin cancer risk due to immunosuppressive therapy
This subgroup allows for a more targeted evaluation of AOM GLP-1 RA use in the population consistent with the medication label and looks at the total number of prescriptions
#Testosterone Interesting finding
PMID 24368434
Clinicians should take a thorough baseline musculoskeletal history before initiating any weight-management pharmacotherapy, including investigational agents such as retatrutide, to allow for meaningful comparison if symptoms arise during treatment
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