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Mol Pain 14:1744806918767697 Aurora SK, Brin MF (2017) Chronic Migraine: An Update on Physiology, Imaging, and the Mechanism of Action of Two Available Pharmacologic Therapies

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What the research shows In the SURMOUNT-1 trial, adults taking once-weekly tirzepatide lost an average of about 15% to 21% of their body weight over 72 weeks depending on dose

Less muscle lost

Eur J Endocrinol (2015) 173:M13357

GLP-1 agonists may exert a centrally mediated effect to reduce addictive behavior at least partly via dopamine modulation