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The study was a systematic literature review and meta-analysis limited to 13 studies, only 3 of which were randomized trials

42 Medullary thyroid cancer There is a theoretical increased risk of medullary thyroid cancer (MTC) as preclinical studies showed a link between GLP-1 receptor agonism to the development of C-cell hyperplasia and MTC in rats and mice

TP53 mutations and survival in squamous-cell carcinoma of the head and neck

However, persistent or unexplained changes might indicate a more serious issue

Healthcare providers can perform targeted assessment including thyroid function tests, cardiovascular evaluation, and review of concurrent medications that might contribute to vasomotor symptoms

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