These findings demonstrate that iron causes photoreceptor degeneration through oxidative stress, with cones being more susceptible than rods (285)
Rastgoo S, Ebrahimi-Daryani N, Agah S, Karimi S, Taher M, Rashidkhani B, et al
Craniofacial abnormalities such as retrognathia, maxillary hypoplasia, or a narrow maxilla can reduce airway patency, thereby increasing the risk of airway obstruction during sleep [4]
The severity usually correlates with dose escalation, meaning higher doses tend to produce more pronounced symptoms initially
A case in point is the so-called glucose-fatty acid cycle, a prime example of tightly coordinated cellular energy metabolism that provides a mechanistic reciprocal regulation of lipid and glucose oxidation to maintain cell homoeostasis and to avoid mitochondrial overloading
Immune dysregulationparticularly involving T-helper cell imbalance, increased pro-inflammatory cytokines (e.g., TNF-, IL-6), and reduced regulatory T cell functionhas been shown to impair maternal-fetal tolerance