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2019;doi:10.1016/S2352-4642(18)30385-7

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Retatrutide's triple-receptor approach offers enhanced metabolic benefits with improved safety profiles, while semaglutide provides established clinical precedents with proven regulatory pathways

However, IL-23, through several signaling pathways, provokes the activation of EMT mechanism, inducing fibrotic processes in autoimmune diseases, and chronic inflammation that determines severe fibrotic evolution in several diseases [239]

The main options currently available include: Orlistat (Alli, Xenical): A lipase inhibitor that reduces dietary fat absorption in the gut