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[DOI] [PubMed] [Google Scholar] 46.Nauck M.A., Siemsglss J., Orskov C., Holst J.J

This aligns with the medication pharmacology, as semaglutide has a half-life of approximately one week, meaning it takes roughly five weeks for the drug to be essentially cleared from your system

STEP-4 trial data demonstrated 14% body weight rebound following Wegovy discontinuation at 68 weeks , establishing clinical justification for long-term GLP-1 therapy that insurers and national health technology bodies are progressively incorporating into obesity management protocols

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References Heffernan, M., Summers, R.J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W.J., & Ng, F.M

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