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JAMA 331 , 15191521 (2024)
However, the clinical utility of native GLP-1 is constrained by its inherent instability, as it is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4), resulting in a very short plasma half-life of approximately two minutes [11]
Thus, expression and staining of key endodermal markers correlate to the observed morphological characteristics, confirming the utility of a morphological based screen
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The mechanism might be related to its own antioxidant properties and GSH activating effect