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Far from being a flaw, this tiny bubble is an engineered element that improves dosing accuracy, minimizes drug waste, and enhances patient comfort

Juvederm came out in 2006 - or received approval by the FDA, based on a clinical trial that determined its safety and efficacy

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Short-term side effects include facial flushing, reduced appetite, nausea, vomiting and, for males, spontaneous erections

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Spreading the same weekly amount across more frequent smaller doses often improves signaling without increasing side effects