The introduction of incretin based therapies, particularly glucagon like peptide 1 receptor agonists, represented a major advance in the management of metabolic disease
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[1] - [4] In vitro studies have highlighted the promising antimicrobial activity of Gly-His-Lys conjugates as candidates for further research into skin and tissue infections
In their seminal study, Peterson and Sullivan utilised a novel non-peptide glucagon receptor antagonist (Bay 27-9955) in healthy, lean males to investigate effects on glycaemia (51)
Furthermore, the GLP-1RA and DPP-IV inhibitor do not usually bring about hypoglycemia and/or weight gain
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