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Proteome analysis reveals candidate markers of disease progression in amyotrophic lateral sclerosis (ALS)

Amir LR, Li G, Schoenmaker T, Everts V, Bronckers AL

Ziech, D., Franco, R., Pappa, A

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Multiple clinical trialsincluding SUSTAIN-6 (semaglutide) and REWIND (dulaglutide)showed significant reductions in major adverse cardiovascular events (MACE) such as: Heart attack Stroke Cardiovascular death This benefit appears to be independent of weight loss , suggesting direct protective effects on the arteries, blood pressure, and cholesterol metabolism