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Une posologie par voie orale de 4 000 g (durant les 2 premiers trimestres de la grossesse) et 5 000 g (durant le 3me trimestre et lallaitement) tous les 15 jours chez les femmes enceintes/allaitantes ayant un apport en vitamine B12 insuffisant

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Symptoms may include: biotin hives (in rare instances) Skin rash (mild) Facial swelling Upset stomach Diarrhea Other Symptoms of Reactions to Too Many B Vitamins An overdose of B vitamins may cause an allergic reaction with symptoms that include: Skin Rash This might appear red with small bumps all over and itchy

This 48-week, phase 2, dose-ranging trial enrolled 338 adults with obesity (BMI 30) but without diabetes, randomising participants to placebo or one of four retatrutide doses: 1mg, 4mg, 8mg, or 12mg administered subcutaneously once weekly

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