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EPAS1 (endothelial PAS domain protein 1) orchestrates transactivation of endothelial ICAM1 (intercellular adhesion molecule 1) by small nucleolar RNA host gene 5 (SNHG5) to promote hypoxic pulmonary hypertension

Mammalian enzyme is a heterodimer made up of a catalytic and a regulatory subunit able to modulate enzyme activity

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Peptides cannot bridge a structural gap without tissue continuity