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50.5% achieved 15% or more STEP 2 (1,210 adults with T2D): 9.6% mean weight loss STEP 3 (with behavioral therapy): 16.0% mean weight loss STEP 5 (2-year data): 15.2% sustained weight loss at 104 weeks Zovaglutide (Phase 2)# Zovaglutide Phase 2 results (presented at EASD 2025) enrolled 303 overweight or obese adults across five dose arms over 24 weeks: Cross-Trial Comparison (Important Caveats)# Zovaglutide's Phase 2 results (10.6-14.4% at 24 weeks) suggest a competitive weight loss trajectory, but several critical differences preclude direct comparison: Duration : 24 weeks (zovaglutide) vs 68 weeks (semaglutide STEP 1)

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Slower dose titration may reduce side effects

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If taken directly before physical effort, l-carnitine promotes the burning of fat reserves and helps improve endurance: the ideal nutritional supplement for all active dieters wishing to lose fat or improve endurance

This should be understood as emerging clinical observation, not established research